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Now more than ever, betting against the overpriced position - which has the easiest like-for-like replacement value to obtain - is your best way to succeed against the market. Welcome back, Zero RB.

The East Region features the betting favorite to win it all in Duke, plus many trendy picks to cause chaos down the bracket. Here are our East Region best bets.

UConn vs Furman play similar styles, but UConn has the talent to advance. But there's a Furman player we're betting on to be a Cinderella guard that gives teams fits in March.

UCLA is a trendy pick in the East region with two awesome offensive players, but UCF fits well against UCLA's defensive scheme. What bets do we like in UCLA vs UCF?

Michigan State vs North Dakota State is going to be a battle of talent, not game plan, as both teams deploy similar styles of play. Will Michigan State hit their shots, and what do we like from a betting perspective here?

Louisville vs South Florida has fireworks written all over it, with both teams loving to play in transition and shoot threes at a high volume.